The global nanotechnology-based medical devices market – the result of the innovative application of semiconductor manufacturing in life sciences and medicine, was valued at around US$ 5 Billion in 2014 and poised to grow at a Compound Annual Growth Rate (CAGR) of around 11-12 % for the next five years period (2014-2019).
In parallel, biomaterials developed impressively in the last three decades, diversifying especially quickly in the last decade. The biomaterials market is poised to reach US$ 130 Billion by 2020, growing at a CAGR of 16% during the forecast period of 2015 to 2020.
Molecular Sense’s development strategy is based on the integrated use of experimental techniques, in particular those originating in the semiconductor technology, coupled with modelling and simulation.
We are offering products, technologies and services in three strategic areas:
1. Diagnostic and high throughput screening microdevices
Molecular Sense developed advanced technical solutions and devices for the better preservation of biomolecular activity on the surfaces of biomedical microdevices. We also developed, in collaboration with Philips Research (via an European grant under Eumina Fab project) designs of surfaces that allow a better signal/noise of the fluorescent signal and thus far better biodetection sensitivity. Molecular Sense has reached a successful result as a proof of concept for its technology. We are looking forward to funding future developments toward a prototype microdevice, inviting private or corporate investors to contact us.
2. Biocomputation and biosimulation
Many technologically and societally important mathematical problems are essentially intractable for traditional, serial computers. We developed a methodology of encoding mathematical problems in geometric networks, which are then explored by biological agents. This research line is via ABACUS research consortium. On February 2016 a breakthrough result in Biocomputation has been published in the Proceedings of the National Academy of Sciences of the United States of America – PNAS Published Paper. More about Biocomputers – proof of concept. This research continues under the new Bio4Comp Project.
3. Biomolecular information processing and databases
Molecular Sense developed advanced methodologies for the representation of molecular surfaces, which have proved superior in predicting the adsorption of biomolecules (e.g., proteins) on artificial surfaces [Here]. The methodology can be used in drug discovery studies. Molecular Sense maintains a comprehensive database (Biomolecular Adsorption Database – BAD) of published data regarding protein adsorption on the surface of biomaterials.